To provide additional confirmation that CDK13 and E2F5 expression are differentially expressed in human PCa, prostatectomy specimens of patients with high-grade PCa (Gleason> 8), low-grade PCa (Gleason< 6) and benign prostatic hyperplasia (BPH) were examined by qRT-PCR and western blot. The gene discussed is E2F5; the disease is posterior cortical atrophy.