PTK2 and posterior cortical atrophy: Importantly, increasing ATF3 via oeATF3 also led to decrease the PTK2 expression in the PCa C4–2, CWR22Rv1 cells (Fig. 4e) and PC-3 cells (Supplementary Fig. 3a), and increase ATF3 via adding ASC-J9® led to decrease the PTK2 expression in the C4–2 and CWR22Rv1 cells (Fig. 4f).