Results showed that there was no statistically significant increase in EGF, IL-1β and IL-6 cytokines, while TNF-α release significantly increased starting from 72 h, and retained up to 1 week, which allows us to affirm that the presence of hA-MSCs can avoid the immune paralysis that often occurs in patients with advanced cirrhosis [60]. This evidence concerns the gene IL1B and Cirrhosis.