Recently, some researchers [4, 5] have proposed that during the progression of keratoconus, the corneal Bowman’s membrane ruptures, resulting in the disorganization of the collagen fibers and imbalance of its material composition, which further caused the corneal protein kinase and other catabolic enzyme levels to increase and the protein kinase inhibitor levels to decrease. This evidence concerns the gene WEE1 and keratoconus.