With regard to clinical factors, univariate analyses included: age (P = 0.590), sex (P = 0.661), type of viral hepatitis (P = 0.693), BCLC stage (P < 0.001), Child–Pugh class (P = 0.037), maximum tumor diameter (P < 0.001), lesion number (P = 0.119), proximity to a large vessel (P = 0.019), proximity to an extrahepatic organ (P = 0.088), AFP (P = 0.369), ALT (P = 0.457), total bilirubin (P = 0.065), GGT (P = 0.205), ALB (P = 0.018), ALP (P = 0.107), and PT (P = 0.269). The gene discussed is AFP; the disease is neoplasm.