Together, our observations provide a neuroanatomical underpinning for recent evidence supporting the importance of calbindin neurons in social and anxiety-like behavior (Harris et al., 2016) and their susceptibility to stressful events (Li et al., 2017) and supports the already emphasized role of parvalbumin neurons in sensory systems and spatial navigation (Atallah et al., 2012; Miao et al., 2017; Runyan et al., 2010; Yu et al., 2016, 2019a). The gene discussed is PVALB; the disease is Anxiety.