STAT3 and neoplasm: The TF–target gene network analysis uncovered an unexpected scenario where both correlation-enhancing genes (with higher correlation in the tumor) and -repressing genes (with lower correlation in the tumor) were targeted by STAT1 (6A), STAT3 (6B), KDM1A (6C), PML (Supplementary Figure 6A) and RELA (Supplementary Figure 6B).