Several cytokines and chemokines contribute to the development of vitiligo and VKH, including type 1 responses (IFNγ, CXCL9/10/11, IL-12, TNF) type 17 responses (IL-17, CCL20, IL-23) and IL-2, which supports T cell growth and survival (13–19). The gene discussed is TNF; the disease is vitiligo.