Of 24 evaluated banked bone marrow aspirate samples of patients with AML, 19 (80%) showed a specific fluorescence intensity (SFI) of >1.0, indicating expression of NKG2D-ligands above the level of the isotype control (SFI=MFI NKG2D-Fc/MFI IgG-Fc) (Figure 3D). Here, KLRK1 is linked to acute myeloid leukemia.