Additionally, since MMP-2 and MMP-9 have been detected in both benign and malignant renal cysts (Harada et al., 2002) and the abnormal expression of MMP-2 and MMP-9 are pertinent to the pathogenesis of atherosclerosis the altered expression and distribution of MMPs might contribute to the correlation between SRCs and CVD (Wagsater et al., 2011). The gene discussed is MMP2; the disease is atherosclerosis.