For example, IL-6 and its receptor IL-6R monoclonal antibody have been used in the treatment of rheumatoid arthritis (Pelechas et al., 2017) and uveitis (Elkinson and McCormack, 2013), and JAK small molecule inhibitors have also been used in the treatment of rheumatoid arthritis and myelofibrosis (Mascarenhas and Hoffman, 2012; Traynor, 2012). This evidence concerns the gene IL6R and rheumatoid arthritis.