ATRX and neuroblastoma: Besides the MYCN-amplified NB case, in which sustained telomere length might be achieved through elevated TERT expression driven by MYCN, all six non-MYCN-amplified cases in our cohort displayed genomic aberrations associated with telomere maintenance or chromatin remodeling; three of these cases had TERT rearrangements, two had ATRX alterations, and one had a mutation in ARID2, which is also part of the SWI/SNF chromatin-remodeling complex.