In a recent article [62] the authors used the multiparameter FACS analysis of immune infiltrate derived from the PP biopsies of severe periodontitis patients and observed that the majority of the immune cells were CD3+ T cells, while among the B cell subpopulations, plasmablasts (CD10−, CD20−, CD38+) and a lesser extent immature B cells (CD10+, CD20+, CD38−) were prominent. The gene discussed is MME; the disease is periodontitis.