“Epithelial-mesenchymal transition” (37% of proteins annotated, 12.6-fold-enrichment) and “Integrin cell surface interactions” (22%, 19.4-fold-enrichment) were the most significantly enriched pathways in the mesothelioma subnetwork (Supplementary Table S11A) but not in the ovarian cancer subnetwork (Supplementary Table S11B), which suggests that the changes in LOX and LOXL interactome associated with cancer might depend on the cancer type. This evidence concerns the gene LOXL3 and mesothelioma.