We found that CgA levels of CRC patients was not associated with any inflammatory markers, however, CgB was positively correlated with interleukin-6 and high sensitivity C reactive protein, supporting the theory that CgA+ and CgA− tumors have different molecular mechanisms, including that the latter are more probably associated with paraneoplastic inflammatory mechanisms, in which interleukin-6 is overproduced. Here, CHGB is linked to colorectal carcinoma.