Despite that there was no difference between the number of major cardiovascular events prior to CRC (p = 0.3831) or in the usage of statins (p = 0.3831) and agents acting on the renin–angiotensin system (p = 0.8947; Table 1), low-density lipoprotein cholesterol (LDL-C) levels were significantly lower in the CgA+ group (p = 0.0119). The gene discussed is REN; the disease is colorectal carcinoma.