PTEN and familial pancreatic carcinoma: Moreover, nine oncogenic pathways were overrepresented among these genes, including oncogenic—Neuregulin, Ephrin receptor, PI3K/AKT, and integrin signaling—and proinflammatory—IL-8, neuroinflammation, and NF-kB signaling—pathways, while the signaling of the tumor suppressor PTEN gene was enriched in pancreatic cancer tissues of mice fed with ERSD.