LY6E and neoplasm: Once tumors reached ~180 mm3, mice were treated with 0.5 or 1.5 mg/kg of anti-Ly6E-CBI or 1.5 mg/kg of anti-Ly6E-MMAE intravenously every 3 weeks up to eight times or until the mice were sacrificed due to body weight loss or overwhelming tumor burden (>1000 mm3).