Three proteins were upregulated in AF samples from women with iSPTD compared with those in women without iSPTD; these included lipocalin-2, S100 A8/A9, and S100 A10, with a density ratio between the groups of 1.7, 1.8, and 1.6, respectively (Fig 2). The gene discussed is LCN2; the disease is atrial fibrillation.