VEGFA and COVID-19: The activation of several downstream pathways would result in various biological effects, such as the maturation of naïve T cells into effector T cells, the expression of vascular endothelial growth factor (VEGF) in endothelial cells, the increase in vascular permeability and reduction of myocardial contractility, which contribute to organ damage and increased risk of death in COVID-19 patients [18].