AFP and infection: Among all variables, three factors significantly correlated with better OS in univariate analysis, including the presence of DM (HR = 0.748, p = 0.001), hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infection (HR = 0.714, p<0.001) and baseline alpha-fetoprotein (AFP) <400 ng/mL (HR = 0.584, p<0.001) (Table 4).