The current study extends previous work that established PPARγ agonism with the T2D drug RSG recues 9MO Tg2576 hippocampus‐dependent associative learning and memory using the background fear conditioning paradigm (Denner et al., 2012; Jahrling et al., 2014; Rodriguez‐Rivera et al., 2011). Here, PPARG is linked to type 2 diabetes mellitus.