However, research has shown that Tmem67 and Bbs8 (a.k.a. Ttc8) mutant ciliopathy models or inner ear-specific Vangl2 mutants showed normal cochlear lengths despite exhibiting severe polarity defects (Abdelhamed et al., 2015; Copley et al., 2013; May-Simera et al., 2015). The gene discussed is TMEM67; the disease is ciliopathy.