The E2F3 expression was remarkably positively related to tumor purity (r = 0.157, P = 5.67e − 04) and infiltrating levels of B cells (r = 0.242, P = 8.88e − 08), CD8+ T cells (r = 0.26, P = 7.74e − 09), and DCs (r = 0.2, P = 1.09e − 05) but no significant correlation with macrophages (r = 0.136, P = 2.98e − 03) or neutrophils (r = 0.15, P = 1.04e − 03) in LGG (Figure 7(c)). Here, CD8A is linked to neoplasm.