Also, the E2F2 expression was significantly positively related to cancer purity (r = 0.172, P = 4.09e − 04) and remarkably negatively related to macrophages (r = −0.183, P = 1.65e − 04), neutrophils (r = −0.305, P = 1.88e − 10), and dendritic cells (r = −0.264, P = 4.23e − 08) but no significant correlation with CD4+ T cells in GBM (Figure 7(b)). The gene discussed is CD4; the disease is cancer.