The E2F5 expression was remarkably positively related to tumor purity (r = 0.382, P = 3.93e − 18), B cells (r = 0.19, P = 2.80e − 05), CD8+ T cells (r = 0.156, P = 6.42e − 04), and DCs (r = 0.182, P = 6.74e − 05) but no significant correlation with macrophages (r = 0.138, P = 2.54e − 03) in LGG (Figure 7(e)). The gene discussed is E2F5; the disease is neoplasm.