E2F2 expression level was remarkably positively related to infiltrating levels of B cells (r = 0.359, P = 5.53e − 16), CD4+ T cells (r = 0.339, P = 3.13e − 14), macrophages (r = 0.285, P = 2.63e − 10), neutrophils (r = 0.293, P = 7.29e − 11), and dendritic cells (r = 0.371, P = 6.15e − 17) but no significant correlation with tumor purity (r = 0.119, P = 8.88e − 03) in LGG (Figure 7(b)). This evidence concerns the gene CD4 and neoplasm.