VEGFA and diabetic macular edema: Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is widely regarded as the standard of care for patients with retinal disease, including neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and macular edema (ME) due to retinal vein occlusion (RVO), and has become the most commonly performed ophthalmic procedure.