TTF1 and lung carcinoma: Based on the above, a miR-7 expression vector under TTF-1 promoter transcriptional control was constructed (p-T-miR-7), this expression vector displayed a reduction of tumor growth rate, migration and metastasis of lung cancer cells in vivo and in vitro suggesting the usefulness of miR-7 to develop new gene therapy strategies selectively against lung cancer (126–128).