We aim to investigate the role of exosomes derived from CXCR4-overexpressing BMSCs in restoring vascular function and neural repair after ischemic cerebral infarction and to clarify the mechanism of these exosomes in promoting angiogenesis and protecting endothelial cells, so as to provide new ideas for the treatments and further mechanism research of stroke. This evidence concerns the gene CXCR4 and stroke disorder.