One-way ANOVA revealed that the CRS and MS + CRS groups had significantly lower PSD95 and synaptophysin protein levels than the control group [PSD95: F(2, 9) = 18.441, P < 0.05, P < 0.001; synaptophysin: F(2, 9) = 26.074, P < 0.05, P < 0.001]. The gene discussed is DLG4; the disease is myeloid sarcoma.