Additionally, there are two ongoing clinical trials, one testing the analgesic efficacy of a TrkA inhibitor on cancer patients with solid tumors or lymphoma (phase I, NCT03556228) and the other measuring the efficacy of anti-NGF monoclonal antibody tanezumab in the treatment of cancer pain due to bone metastasis in patients already taking background opioid therapy (phase III, NCT02609828). This evidence concerns the gene NTRK1 and cancer.