Meta-analysis from published database demonstrated that TRPM7 expression is significantly increased in anaplastic astrocytoma patients (t-test: 1.928; p-value: 0.031; n = 19; Figure 1B), diffuse astrocytoma patients (t-test: 2.011; p-value: 0.040; n = 7; Figure 1C), and glioblastoma patients (t-test: 3.368; P-value: 7.72E-4; n = 8; Figure 1D) compared to that of normal brain controls (n = 23). This evidence concerns the gene TRPM7 and glioblastoma.