TRPM7 and central nervous system cancer: As shown by the Western blot, all glioma cell lines A172, U87MG, U373MG, SF767, and SNB19, as well as two cell lines resistant to TMZ, T98G, and LN18, express an almost equal amount of TRPM7 with U87MG and SNB19 having slightly lower levels of expression (Figure 3A).