Myeloid cell-specific deletion of genes involved in autophagosome elongation and LC3-associated phagocytosis [LAP, reviewed in (Heckmann and Green, 2019)] enhanced anti-tumor immunity, attenuating tumor growth and metastasis in multiple syngeneic tumor models (Alissafi et al., 2018; Cunha et al., 2018). The gene discussed is MAP1LC3A; the disease is neoplasm.