uPAR has been shown to be involved in nearly every step of cancer metastasis, including cell migration (Schiller et al., 2009), adhesion (Andreasen et al., 1997; Liang et al., 2008), angiogenesis (Mignatti and Rifkin, 1995), and invasion (Subramanian et al., 2006; Kunigal et al., 2007). This evidence concerns the gene PLAUR and cancer.