Acute myeloid leukemia (AML) with co-existing NUP98-NSD1 and FLT3-ITD mutation is accompanied by poor prognosis and a low chance of survival (Akiki et al., 2010; Hollink et al., 2011; Ostronoff et al., 2014; Thanasopoulou et al., 2014). This evidence concerns the gene NSD1 and acute myeloid leukemia.