IGF1 and colitis: As concluded elsewhere in the context of colitis, the inflammation-ameliorating mechanisms of AG include (i) the attenuation of systemic innate and adaptive immune responses, which is dependent on the direct suppression of leukocytes; (ii) the AG-stimulated liberation of tissue-strengthening GH and insulin-like growth factor 1 (IGF-1) and (iii) the elevation of the intestinal blood flow and motility, thus reducing the contact time of inflammatory irritants with the intestinal mucosa (Baatar et al., 2011; Deboer, 2011).