CD36 and arteriosclerosis: Moreover, the prolonged daily injection of the CD36-favoring ghrelin derivate EP 80317 dramatically ameliorated the development of vascular lesions in the apoE−/− animal model of arteriosclerosis by lessening the CD36-driven endocytosis of oxidized low density lipoprotein (oxLDL) by macrophages (Marleau et al., 2005).