Interestingly, the AGT promoter has two putative binding sites for the transcription factor high-mobility group AT-hook 1 (HMGA1) at positions −996 and −651 (Fig. S5A) and we find in Fig. 7A that HMGA1 expression was elevated in both A549 and H460 lung cancer cells. The gene discussed is HMGA1; the disease is lung carcinoma.