Conjugates were then evaluated for binding to a panel of cell lines to determine whether p700 enhances binding of Doxil to mouse and human breast tumour cell lines (4T1 and MCF-7, respectively) or a mouse endothelial cell line (H5V) known to highly express VEGFR2, relative to human primary microvascular endothelial cells (HuDMEC). Here, KDR is linked to breast neoplasm.