RPS6KB1 and type 2 diabetes mellitus: 8-PG has been suggested to protect against type 2 diabetes mellitus (T2DM) elated metabolic dysfunctions in a mouse model [12], to show anticancer activity in U-118 MG cells [13], and to modulate the phosphorylation of PI3K, Akt, and P70S6K1 in myotube cells promoting a better recovery from muscle atrophy [14].