We analyzed the relationship between the severity of depression according to the BDI and the frequency of the genotypes of the 44-bp VNTR polymorphism in the 5-HTT gene (SLC6A4) promoter region and the 30-bp VNTR polymorphism in the MAO-A gene (MAOA) promoter region. The gene discussed is SLC6A4; the disease is depressive symptom measurement.