The detailed mechanism of the complicated signaling cascade has been widely investigated in several cancers for the purpose of using KLF10 as a reliable prognostic index of cancer progression [14,15,16,17,18,19], and the significant prognostic value of KLF10 as a biomarker for predicting the survival of patients with pancreatic adenocarcinoma has been demonstrated in previous studies [7]. The gene discussed is KLF10; the disease is pancreatic adenocarcinoma.