DES and neoplasm: Figure S6 shows that only one tumor section with mainly desmin positive cells had a homozygous WT1 mutation (Figure S6A, lane 2). All other dissected areas contained mutant and wild type WT1 and the normal section is wild type for WT1 (Figure S6A, lane5). Figure S6B shows that all sections except for the normal kidney (lane 5) contain mutant and wild type CTNNB1 in variable concentrations.