However, the clinical signs and the results of the diagnostic investigations (ultrasound hepatic and peri-hepatic changes, an elevated marker of liver injury-ALT, raised total bilirubin and jaundice, hyperglobulinemia and poor coagulation (namely severe subcutaneous haemorrhage and increased prothrombin time (PT) and activated partial thromboplastin time (aPTT)) are all compatible with Rabbit Haemorrhagic Disease. Here, F2 is linked to Jaundice.