NLRP1 and asthma: Gathering all known disease associations for this allele, it is clear that a protective/causative role is not always consistent with inflammasome inhibition/activation, respectively (Table III).53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88 Therefore, we suggest that in conditions such as asthma, where M1184V contributes to disease but NLRP1 has a protective role, the underlying mechanism of activation for NLRP1 resembles DPP9 inhibition.