We then performed single-variant association testing, using logistic regression, to assess the impact of the 3 nonsynonymous NLRP1 polymorphisms in haplotype 2A—L155H (rs12150220), V1059M (rs2301582), and M1184V (rs11651270)—on asthma status in our study population. This evidence concerns the gene NLRP1 and asthma.