TGFB1 and pulmonary fibrosis: We have also shown that the expression of sialidase mRNA levels are not a good predictor of protein expression, as TGF-β can modulate NEU3 protein levels by decreasing NEU3 degradation and by increasing the translation of NEU3 mRNA, explaining the apparent paradox of high levels of NEU3 protein in pulmonary fibrosis without a concomitant increase in the expression of NEU3 mRNA [119].