While both CXCR3 isoforms are upregulated during ZIKV infection, CXCR3-A is significantly more abundant on prostate epithelial cells during early infection with ZIKV-FLA or FLR propagated in one cell type (referred to as FLA/1 and FLR/1) (Fig 7A). This evidence concerns the gene CXCR3 and Zika virus infectious disease.