Deep proteomic analysis of a panel of 50 intestinal cancer cell lines shows that caspase-4 and GSDMD are constitutively expressed, while NLR family pyrin domain containing 3 (NLRP3), gasdermin E (GSDME), and caspase-5 are undetectable under standard growth conditions [39]. This evidence concerns the gene NLRP3 and intestinal cancer.