DACH1 and carcinosarcoma: We first compared tumor mutation counts in the TCGA PCA endometrial cancer and carcinosarcoma cohorts between DACH1 mutated patients and wild-type and found clinically significant differences with a median of 8972 in DACH1 mutants vs. 65 in DACH1 wild-type (p-value = 7.35e-09).