The most frequently reported TEAEs overall (4 or more subjects [5.4%]) were contact dermatitis (31 subjects [41.9%]), decreased hemoglobin (30 subjects [40.5%]), headache (17 subjects [23.0%]), nausea (8 subjects [10.8%]), ECG QT prolonged (6 subjects [8.1%]), increased alanine aminotransferase (6 subjects [8.1%]), dizziness (5 subjects [6.8%]), increased aspartate aminotransferase (4 subjects [5.4%]), protein in urine (4 subjects [5.4%]), and ecchymosis (4 subjects [5.4%]); see Table 2. This evidence concerns the gene GPT and contact dermatitis.