However, the expression of lipogenic factors (peroxisome proliferator‐activated receptor‐gamma (pparγ), sterol regulatory element binding proteins‐1 (srebf1) and MLX interacting protein (mlxip)) was increased in diet‐induced obesity (DIO) compared to NOR in the [HBx,src] transgenic fish, and OF treatment significantly reduced the expression (Figure 1A). This evidence concerns the gene PPARG and obesity due to melanocortin 4 receptor deficiency.