These included focal adhesion, extracellular matrix (ECM)-receptor interaction, pathways in cancer, phosphatidylinositol 3-kinase (PI3K)-Akt, mitogen-activated protein kinase (MAPK), transforming growth factor β (TGF-β), and hypoxia-inducible factor 1 (HIF-1) signaling pathways, and glycolysis/gluconeogenesis (Figures 3B and S4B). The gene discussed is AKT1; the disease is cancer.