KL and Stroke: Moreover, the Cox proportional models adjusted for established risk factors, kidney function, and the severity of stroke revealed that each 100 pg/mL increase in soluble α-Klotho levels was associated with decreased OS (HR = 0.951 (0.908–0.995), p < 0.05) and SFS (HR = 0.949 (0.908–0.993), p < 0.05).