Overexpression of TRPV2 was not observed in stationary primary solid tumors at stages T2a and T2b, but it was noticeable in metastatic tumors at stage M1 as well as in metastatic PCa cell lines PC3 and DU-145 derived from the bone and the brain, respectively [62, 63]. Here, TRPV2 is linked to posterior cortical atrophy.